会议预告|SMART Symposium智能生物与医药研讨会
SMART Symposium
AI-driven Computational Biology and Medicine
智能生物与医药
Organized by Shenzhen Medical Academy of Research and Translation (SMART)
Shenzhen Bay Laboratory (SZBL)
Shenzhen, China
October 26 - 29, 2024
随着科技的飞速发展，生物医药领域正经历着前所未有的融合与创新，在涵盖传统生物学研究精髓的同时，还深度融合人工智能、大数据、云计算等现代信息技术，为医药研发、疾病诊疗及健康管理带来重大突破。在本次研讨会中，我们召集领域内顶尖专家和学者，深入探讨相关领域最新研究成果。
With the rapid development of technology, the field of biomedicine is undergoing unprecedented integration and innovation. While encompassing the essence of traditional biological research, it also deeply integrates modern information technologies such as artificial intelligence, big data, and cloud computing. This integration has brought about significant breakthroughs in pharmaceutical research, disease diagnosis and treatment, and health management. In this symposium, we have convened top experts and scholars in the field to delve into the latest research findings in related areas.
会议将围绕计算生物学、药物设计、人工智能、结构预测等方面展开讨论，以期能够为智能生物与医药相关领域的发展提供建议。
The conference will focus on topics such as computational biology, drug design, artificial intelligence, and structure prediction, with the aim of providing suggestions for the development of intelligent biological and pharmaceutical-related fields.
会议信息
CONFERENCE INFORMATION
会议时间：2024年10月26日-29日
会议地点: 深圳光明云谷国际会议中心
报名截止时间：2024年10月23日18:00
参会方式：线下
会议语言：英语
Date：October 26-29, 2024
Venue: Shenzhen Guangming Cloud Valley Inter national Conference Center
Deadline for Registration: 18:00 on October 23, 2024
Participation：In-person
Language: English(No simultaneous interpretation)
会议主题
CONFERENCE THEME
高加力
Jiali Gao
明尼苏达大学 | 深圳湾实验室
University of Minnesota | Shenzhen Bay Laboratory
周耀旗
Yaoqi Zhou
深圳湾实验室
Shenzhen Bay Laboratory
彭琴
Qin Peng
深圳湾实验室
Shenzhen Bay Laboratory
会议日程：
Saturday, October 26, 2024
14:30-22:00
Registration and hotel check-in
Sunday, October 27, 2024
8:20-8:50
Sign-in
8:50-9:00
Moderator: Jiali Gao
Welcome speech：Jiali Gao
Session 1: Single Cell
9:00-9:45
Yanyi Huang
Peking University
Spatially resolved RNA analysis
9:45-10:15
Sheng Zhong
University of California, San Diego
Single-cell multiplex chromatin and RNA interactions in ageing human brain
10:15-10:45
Pan Deng
Microsoft Research AI for Science
Directing cellular transition on gene graph-enhanced cell state manifold
10:45-11:10
Coffee Break+ Group Photo
Session 2: AI and Big data
11:10-11:40
Xuhui Huang
University of Wisconsin-Madison
Leveraging Protein Dynamics Memory with Machine Learning to Advance Drug Design: From Antibiotics to Targeted Protein Degradation
11:40-12:10
Ya Zhang
Shanghai Jiao Tong University
Advancing Medical Generalist Artificial Intelligence Models
12:10-13:30
Lunch
Session 3: Computational Genomics
13:30-14:00
Kaifu Chen
Harvard Medical School
Method for Discovering Cell Differentiation Factors Based on AI and Gene Expression Regulatory Mechanisms
14:00-14:30
Yi Xing
University of Pennsylvania
Long-read RNA-seq strategies to study human diseases
14:30-15:00
Jingzhi Pu
Indiana University Indianapolis
Gaussian process facilitated QM/MM simulation
15:00-15:20
Coffee Break
Session 4: Computational Enzyme Design
15:20-16:05
Kendall N. Houk
University of California，Los Angeles
Computational Exploration of Mechanisms of Catalysis by Novel Enzymes
16:05-16:35
Jingyi Jessica Li
University of California，Los Angeles
ClusterDE: a double-dipping-robust method for identifying reliable marker genes of cell types and spatial domains
16:35-17:05
Vicent Moliner
Institute of Advanced Materials (INAM)
University Jaume I
Towards the design of enzyme inhibitors from QM/MM computational studies
17:05-17:35
Yun-Dong Wu
Peking University
Towards Effective Studies of Cyclic Peptides and Protein-Peptide Interaction-based Drug Design
17:35-18:05
Suwen Zhao
ShanghaiTech University
Discover novel DNA modifications in bacteriophages through enzyme function prediction
18:05-18:35
Poster
Monday, October 28, 2024
Session 5: Drug Design I
9:00-9:45
William L. Jorgensen
Yale University
Evolution of Computer-Aided Drug Discovery
9:45-10:15
Linfeng Zhang
DP Technology
Towards a large atomic model-centric ecosystem for micro-scale modeling and design
10:15-10:45
Niu Huang
National Institute of Biological Sciences, Beijing
Harnessing the Power of Physics and Data: Models in Structure-Based Drug Discovery
10:45-11:05
Coffee Break
Session 6: AI of the Nucleus
11:05-11:35
Maria Pia Cosma
Centre for Genomic Regulation (CRG), Barcelona, Spain.
AI of the Nucleus (AINU) identifies cell heterogeneity based on the nanoscale spatial arrangement of chromatin
11:35-12:05
Maria Carolina Florian
IDIBELL Bellvitge Biomedical Research Institute
Reducing nuclear stretching rejuvenates aged hematopoietic stem cells
12:05-13:30
Lunch
Session 7: Structure & Dynamics
13:30-14:00
Yi Qin Gao
Peking University
Integrating diverse experimental data in protein structure prediction and pre-trained model of protein structures
14:00-14:30
Guanghong Wei
Fudan University
Exploring the molecular mechanisms of pathological mutations in enhancing the phase separation of amyloid proteins
14:30-15:00
Jie Yan
National University of Singapore
Unveiling Mechanosensing Mechanisms of Proteins through AI-Based Structural Prediction, Molecular Dynamics Simulations and Single-Molecule Manipulation
15:00-15:30
Guohui Li
Liaoning Normal University
A Multipole-based Reactive Force Field for Hydrocarbons
15:30-15:50
Coffee Break
Session 8: Drug Design II
15:50-16:35
Teresa Head-Gordon
University of California，Berkeley
A systematic physics-based machine learning workflow to create and evaluate potency of drug molecules
16:35-17:05
Mark von Itzstein
Griffith University
Clinically-significant respiratory viruses and drug discovery
17:05-17:35
Luhua Lai
Peking University
Protein allosteric regulation and AI assisted functional protein design
17:35-18:05
John Z.H. Zhang
Shenzhen University of Advanced Technology
Protein-ligand binding free energy and molecular solvation
Tuesday, October 29, 2024
Session 9: AI - A New Frontier of Biomedical Computation
Moderator:
9:00-9:45
Modesto Orozco
Institute for Research in Biomedicine
University of Barcelona
Nucleic acids at the edge between AI and simulation techniques.
9:45-10:15
Jing-Dong jackie Han
Peking University
AI and Aging
10:15-10:45
Wei Li
University of California, Irvine
Harnessing Tandem Repeats to Elucidate the Genetic of Human Health and Disease
10:45-11:05
Coffee Break
Session 10:Generative AI
11:05-11:35
Wei Liu
Tencent AI Lab
What's Next for LLMs and Generative AI Research
11:35-12:05
Lihao Wang
ByteDance
ConfDiff: Protein Conformation Generation via Force-Guided SE(3) Diffusion Models
12:05-13:30
Lunch
Session 11: Everything AI
13:30-14:00
Kelin Xia
Nanyang Technological University
Mathematical AI for Molecular Sciences
14:00-14:30
Jing Ma
Nanjing University
Hydroxyapatite Nanoparticles: Growth Mechanism and Surface Stability
14:30-15:00
Jun Jiang
University of Science and Technology of China
A data driven robotic AI-chemist
15:00-15:30
Tieyan Liu
Microsoft Research AI for Science
TBD
15:30-16:00
Wei Yang
Florida State University
TBD
16:00-16:30
Closing ceremony: Yaoqi Zhou
会议注册
REGISTRATION
1.请于2024年10月23日18:00前通过网站填写注册信息： https://symposia.smart.org.cn
2.会议注册费
参会者身份
注册费
学生(凭学生证)
1640元/人
学术
2000元/人
企业
2500元/人
3.注册成功后会议主办方将会通过邮件通知您，请您注意查收。
1. Please fill in your registration information before 18:00 on October 23, 2024 via the website:
https://symposia.smart.org.cn
2. Registration fee
Category
Registration Fee (CNY/USD)
Student
CNY 1,640（USD 230）
Academic
CNY 2,000（USD 280）
Corporate
CNY 2,500（USD 350）
3. After successful registration, you will receive an email notification, please kindly check it.
注：
1. 会议不设现场报名，请于2024年10月23日18：00前完成报名与缴费。
2. 注册费电子发票将于确认到款后15个工作日内发送至注册邮箱。
3. 10月25日18:00后将无法申请退款。
Notice：
1. The conference does not accept on-site registration. Please complete the registration and payment before 18:00 on October 23, 2024.
2. The electronic invoice for the registration fee will be sent to the registered email address within 15 working days after the payment is confirmed.
3. Refunds will not be available after 18: 00 on Oct. 25th
墙报环节
POSTER SESSION
本次会议设有墙报展示环节，并设优秀墙报奖。我们诚邀您提交题目，参与墙报展示会（鼓励展示最新研究进展或未发表的研究课题）。
This conference will feature a poster presentation session, with an award for outstanding posters. We sincerely invite you to submit your topics and participate in the poster presentation (latest research advancements or unpublished research topics are encouraged).
参与方式：在注册网址中上传墙报信息
墙报要求：若您参与墙报展示，请自行打印并携带至会议现场，交由工作人员在指定位置张贴
墙报规格：宽80 cm×高120 cm
墙报申请截止日期：2024年10月23日18：00
How to participate: Upload poster information to the registration website.
Poster requirements: If you participate in the poster presentation, please print the poster yourself and bring it to the conference venue to be posted in the designated area by the staff.
Poster size: Width 80 cm×Height 120 cm
Deadline: 18:00 on Oct. 23, 2024
会议住宿
ACCOMMODATION
本次会议不统一安排住宿，参会代表可自行联系附近酒店
We do not provide centralized accommodation for this conference. Participants can arrange their own accommodation by contacting nearby hotels.
住宿推荐
Recommended Hotels
深圳光明天安云谷逸衡酒店
EVEN Hotels Shenzhen Guangming Cloud Park, an IHG Hotel
地址：深圳市光明区新湖街道圳美社区圳园路98号（距离会场500米）
Address: No.98 Zhenyuan Road, Zhenmei Community, Xinhu Street, Guangming District, Shenzhen.
(500 meters away from the conference venue)
联系人：何经理 13242057885
Contact: Manager He 13242057885
深圳光明天安云谷智选假日酒店
Holiday Inn Express Shenzhen Guangming Cloud Park, an IHG Hotel
地址：深圳市光明区圳美大道68号（距离会场500米）
Address: No.68 Zhenmei Road, Guangming District, Shenzhen
(500 meters away from the conference venue)
联系人：何经理 13242057885
Contact:Manager He 13242057885
深圳光明中集行政公寓酒店
Guangming CIMC Executive Apartments Hotel
地址：深圳市光明区凤凰街道侨明路中集行政公寓酒店（距离会场 7.5 公里）
Address: CIMC Executive Apartments Hotel, Qiaoming Road, Fenghuang Street, Guangming District, Shenzhen
( 7.5 kilometers away from the conference venue)
联系人：卢经理13826592644
Contact: Manager Lu 13826592644
会议咨询
CONTACT
If you have any question, please contact；
周老师 Xinghua Zhou 15012578593 zhouxingh@szbl.ac.cn
向老师 Tania Xiang 13591397049 symposium@smart.org.cn
会议时间 2024-10-26至2024-10-29 会议地点 广东深圳
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